For me, immersion is what makes or breaks video-games. I'm looking forward to getting lost in Night City, walking around just taking in the sights and hearing, breathing, and feeling the city throughout the day and night. Lore is another thing I love and can't wait to learn more about the cyberpunk universe by reading in-game and playing through the story and side-quests.
From past experience with CDPR, I'm expecting to be gripped by twisted plot points within the story, alongside the atmosphere surrounding the story which immerses you in the world.
I really want to be taken into a new world again, that's what I'm mostly looking forward to!
To be honest, the thing I'm looking forward to the most is the genitalia customisation for your character (immature I know 😆 but it's one of the things I miss doing in Saints Row 4). It'd be interesting to see how CD Projekt Red would go on about implementing it and its potential effects on dystopian future setting of the game.