I'm most looking forward to immersing myself in the Cyberpunk setting. I've tried other games with a cyberpunk theme, such as Shadowrun, but couldn't quite get into them.
Knowing CD Projekt's fantastic work they did with The Witcher, I'm confident that Cyberpunk 2077 will be reeling me in immediately and will keep me immersed for hundreds of hours.
Thanks CD Projekt and PC Gamer!