Got to play with Guido this morning, as his classes haven't started yet. I'm going to cut a fairly long story short (a first for me) by just saying we were in a boss fight, and I went down, and Guido came over to revive me, but ate me instead. Just another weird moment in a supremely weird game.
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After you reach a certain point, you can pick a secondary class. My main class is the Medic because, well, I take lots of damage. For a second class, I initially picked the Handler who has a dog companion who draws aggro, deals damage and will attempt to revive you when you are down. I decided to test the revive, and he just sat next to me and stared at me. After looking it up, I discovered that he only revives you if Handler is your primary class.
So I decided to switch to the Engineer, who gets boosts to armor and can set down turrets. That's pretty fun.
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There are so many options in this game for your loadout that I just now (27 hours in) decided upon my preferred weapons and weapon mods (until, at least, I get more options). I was using a sniper rifle as my main gun, but I've come to realize that my machine gun has too many advantages not to use it. I've put the Bore mod on it, which creates a weak spot on the enemy. The mutator on that gun gives escalating bonuses to critical, which is great for a weapon that shoots that fast.
On my pistol, I'm using the machine pistol that you get off of the freighter in The Ward. My mod on it is "Hot Shot", and it does tremendous damage. It's really the only pistol worth anything that I've found so far. The mutator I'm using returns 20 percent of my spent ammo, which is nice.