A quick update - although it seems I may be the only one playing Nightreign so this may just be going into the void
After 22 hours in game I have felled half of the Nightlords, and am now working on what many are saying is the toughest boss in the game, The Equilibrius Beast: Libra, Creature of the Night (name long enough for ya?)
I have only queued with random players and have had a pretty good mix of skill levels, but mostly people are pretty damn good at the game which helps A LOT! There is a game mechanic called "Shifting Earth" where parts of the map change to open up new challenges and run altering rewards. It's really cool, but honestly there's no way I'd be able to figure some of them out without a guide or having someone walk me through them (which has been my preferred way, I like the hand-holding!).
Anyway, Libra is proving to be my Malenia for Nightreign. Hopefully I can eek out a win eventually!